The dissertation is devoted to the development and justification of an automated ultrasonic therapy system for the human eye, intended for non-invasive therapeutic impact on biological tissues aimed at treatment and stimulation of regenerative processes.
The object of the research is the process of ultrasonic transducer interaction with the tissues of the human eye.
The subject of the research is methods for improving the efficiency of therapeutic ultrasound.
The scientific novelty lies in the creation of a universal multifunctional system for generating therapeutic signals and a new design of an ultrasonic transducer with increased efficiency in human eye therapy, as well as in the development of a method for continuous contact monitoring during therapy.
The work presents an analytical review of modern therapeutic ultrasound methods, in particular LIPUS, Li-ESWT, and UMUS, and examines the mechanisms of micro-energy effects on cells involved in regenerative medicine.
In the second chapter, the justification and design of the acoustic part of the system are carried out. The objects of ultrasonic exposure (optic nerve, macula, retina) are identified, the acoustic layers of the eye are studied, and the parameters of the piezoelectric element, cutoff frequencies, attenuation, and near-field dimensions are calculated. A design of an ultrasonic transducer for operation with a broadband sinc signal from 0 to 20 MHz is proposed, ensuring efficient energy transmission in contact with the cornea.
In the third chapter, the electrical part of the system is justified and developed. It includes an arbitrary waveform signal generator based on high-speed ADCs/DACs, pre-amplification and power amplification stages, a protection circuit, as well as a continuous contact monitoring mechanism between the transducer and the eye surface based on phase variation of the signal. The operating algorithm of the device with automatic regulation of therapy parameters is described.
In the fourth chapter, a startup project for commercialization of the device is developed, including an idea audit, competitiveness analysis, value proposition, business model, team project, implementation schedule, and marketing strategy. It is shown that the product has high market attractiveness due to its low cost, multifunctionality, and the ability to implement various types of ultrasonic therapy within a single device.
Research advisor: V.Bazhenov